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Michiaki Unno Selected Research

Neoplasms, Cystic, Mucinous, and Serous

3/2021Serine/Threonine Kinase 11 Plays a Canonical Role in Malignant Progression of KRAS-mutant and GNAS-wild-type Intraductal Papillary Mucinous Neoplasms of the Pancreas.
10/2020GNAS mutation detection in circulating cell-free DNA is a specific predictor for intraductal papillary mucinous neoplasms of the pancreas, especially for intestinal subtype.
11/2018Steroidogenesis in ovarian-like mesenchymal stroma of hepatic and pancreatic mucinous cystic neoplasms.
9/2017Pancreatic neuroendocrine tumor with complete replacement of the pancreas by serous cystic neoplasms in a patient with von Hippel-Lindau disease: a case report.
5/2016Immunohistochemical analysis of steroidogenic enzymes in ovarian-type stroma of pancreatic mucinous cystic neoplasms: Comparative study of subepithelial stromal cells in intraductal papillary mucinous neoplasms of the pancreas.
1/2014A GNAS mutation found in pancreatic intraductal papillary mucinous neoplasms induces drastic alterations of gene expression profiles with upregulation of mucin genes.
11/2013Dilated papilla with mucin extrusion is a potential predictor of acute pancreatitis associated with intraductal papillary mucinous neoplasms of pancreas.
2/2013One of the multifocal intraductal papillary mucinous neoplasms with the clinical characteristics of mucinous cystic neoplasm.
2/2012Clinicopathological characteristics and molecular analyses of multifocal intraductal papillary mucinous neoplasms of the pancreas.
12/2011Somatic mutations in PIK3CA and activation of AKT in intraductal tubulopapillary neoplasms of the pancreas.
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Michiaki Unno Research Topics

Disease

185Neoplasms (Cancer)
10/2022 - 08/2002
81Pancreatic Neoplasms (Pancreatic Cancer)
04/2022 - 01/2006
50Neoplasm Metastasis (Metastasis)
06/2022 - 04/2008
29Carcinoma (Carcinomatosis)
12/2021 - 06/2004
28Adenocarcinoma
03/2022 - 08/2011
22Cholangiocarcinoma
01/2021 - 11/2003
17Colorectal Neoplasms (Colorectal Cancer)
01/2021 - 01/2008
14Inflammation (Inflammations)
05/2022 - 05/2003
14Lymphatic Metastasis
02/2022 - 04/2008
14Neoplasms, Cystic, Mucinous, and Serous
03/2021 - 01/2007
13Hemorrhage
06/2022 - 07/2011
10Colonic Neoplasms (Colon Cancer)
12/2021 - 01/2008
10Rectal Neoplasms (Rectal Cancer)
12/2021 - 11/2014
10Stomach Neoplasms (Stomach Cancer)
10/2020 - 01/2005
9Pathologic Constriction (Stenosis)
03/2022 - 01/2011
9Melanoma (Melanoma, Malignant)
02/2018 - 11/2016
8Pancreatitis
04/2022 - 01/2008
8Thrombosis (Thrombus)
03/2022 - 11/2006
8Breast Neoplasms (Breast Cancer)
04/2021 - 01/2007
7Klatskin Tumor
07/2022 - 07/2010
7Neuroendocrine Tumors (Neuroendocrine Tumor)
02/2022 - 01/2015
7Esophageal Neoplasms (Esophageal Cancer)
02/2022 - 03/2018
7Pancreatic Fistula (Pancreatic Fistulas)
01/2021 - 07/2011
7Chronic Pancreatitis
02/2019 - 10/2010
6Head and Neck Neoplasms (Head and Neck Cancer)
06/2022 - 11/2017
6Diabetes Mellitus
06/2021 - 03/2011
6Carcinogenesis
01/2019 - 07/2011
5Sclerosing Cholangitis
07/2022 - 09/2020
5Residual Neoplasm
05/2022 - 11/2015
5Cholangitis
04/2022 - 09/2013
5Fibrosis (Cirrhosis)
04/2022 - 01/2017
5Body Weight (Weight, Body)
03/2022 - 01/2013
5Esophageal Squamous Cell Carcinoma
02/2022 - 03/2018
5Hepatocellular Carcinoma (Hepatoma)
01/2022 - 11/2006
5Infections
01/2022 - 11/2003
5Pancreatic Intraductal Neoplasms
03/2021 - 12/2011
5Reperfusion Injury
07/2020 - 01/2002
4Sarcoma (Soft Tissue Sarcoma)
05/2022 - 04/2008
4Death (Near-Death Experience)
03/2022 - 07/2020
4Hypoxia (Hypoxemia)
03/2022 - 01/2002
4Heart Failure
11/2021 - 03/2004
4Esophageal Achalasia (Megaesophagus)
09/2021 - 01/2020
4Necrosis
04/2021 - 01/2019

Drug/Important Bio-Agent (IBA)

38GemcitabineFDA Link
02/2022 - 09/2007
29Proteins (Proteins, Gene)FDA Link
06/2021 - 01/2004
22Pharmaceutical PreparationsIBA
12/2021 - 08/2005
15Messenger RNA (mRNA)IBA
10/2021 - 03/2002
11L-methionine gamma-lyaseIBA
01/2021 - 10/2017
10AntigensIBA
08/2020 - 11/2013
9EnzymesIBA
04/2022 - 07/2012
9CarbohydratesIBA
05/2020 - 05/2011
8Fluorouracil (Carac)FDA LinkGeneric
02/2022 - 10/2005
8Methionine (L-Methionine)FDA Link
01/2021 - 10/2017
8Glucose (Dextrose)FDA LinkGeneric
01/2021 - 05/2007
8Biomarkers (Surrogate Marker)IBA
12/2020 - 09/2015
8Biological ProductsIBA
04/2020 - 06/2007
8MucinsIBA
01/2020 - 11/2007
7Paclitaxel (Taxol)FDA LinkGeneric
02/2022 - 07/2007
7Tumor Biomarkers (Tumor Markers)IBA
08/2021 - 11/2006
7CateninsIBA
06/2021 - 12/2010
6130-nm albumin-bound paclitaxelIBA
02/2022 - 11/2017
6Immunoglobulin G (IgG)IBA
10/2021 - 09/2007
6Insulin (Novolin)FDA Link
01/2021 - 01/2009
6Bile Acids and Salts (Bile Acids)IBA
01/2018 - 10/2007
5Cetuximab (Erbitux)FDA Link
06/2022 - 10/2011
5Doxorubicin (Adriamycin)FDA LinkGeneric
05/2022 - 08/2005
5DNA (Deoxyribonucleic Acid)IBA
04/2022 - 07/2011
5dicarboxydine (DCD)IBA
03/2022 - 01/2018
5Cisplatin (Platino)FDA LinkGeneric
02/2022 - 10/2005
5Transcription Factors (Transcription Factor)IBA
01/2022 - 09/2008
5Adenosine Triphosphate (ATP)IBA
11/2021 - 12/2016
5Phosphotransferases (Kinase)IBA
01/2021 - 07/2014
5Small Interfering RNA (siRNA)IBA
04/2020 - 04/2008
5Temozolomide (Temodar)FDA LinkGeneric
01/2018 - 12/2016
5Protein Isoforms (Isoforms)IBA
01/2018 - 06/2007
5Cadherins (E-Cadherin)IBA
08/2015 - 04/2008
4Therapeutic UsesIBA
12/2020 - 07/2014

Therapy/Procedure

60Therapeutics
04/2022 - 01/2002
49Drug Therapy (Chemotherapy)
06/2022 - 10/2005
46Pancreatectomy
06/2022 - 01/2007
41Neoadjuvant Therapy
07/2022 - 11/2009
23Pancreaticoduodenectomy
10/2022 - 01/2007
20Hepatectomy
01/2022 - 01/2010
11Liver Transplantation
07/2022 - 09/2017
11Adjuvant Chemotherapy
12/2021 - 12/2011
10Gastrectomy
01/2021 - 01/2005
9Esophagectomy
05/2022 - 03/2018
8Chemoradiotherapy
05/2022 - 11/2017
7Lymph Node Excision (Lymph Node Dissection)
06/2022 - 11/2013
7Immunotherapy
01/2021 - 02/2003
6Radiotherapy
10/2021 - 10/2005
6Stents
12/2020 - 10/2005
6Pancreaticojejunostomy
07/2020 - 10/2010
5Laparotomy
03/2022 - 06/2013
5Transplantation
03/2022 - 12/2011
5Islets of Langerhans Transplantation
01/2015 - 01/2012
4Aftercare (After-Treatment)
05/2022 - 11/2013
4Operative Surgical Procedures
05/2022 - 06/2020
4Myotomy
09/2021 - 01/2020
4Operative Time
11/2020 - 10/2015